Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 15/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678594 | 0.91 | MAOA (0.54) | GRM2MAOAMAOBHSD11B1 | |
| SCHEMBL9844079 | 0.90 | GRM2 (0.60) | GRM2 | |
| SCHEMBL9844097 | 0.89 | GRM2 (0.55) | GRM2 | |
| SCHEMBL9844472 | 0.86 | GRM2 (0.50) | GRM2 | |
| SCHEMBL9844402 | 0.85 | GRM2 (0.44) | GRM2 | |
| SCHEMBL9844356 | 0.84 | GRM2 (0.52) | GRM2 | |
| SCHEMBL9844255 | 0.84 | GRM2 (0.52) | GRM2 | |
| SCHEMBL9844288 | 0.83 | GRM2 (0.53) | GRM2 | |
| SCHEMBL9844119 | 0.82 | GRM2 (0.56) | GRM2MAOAMAOBHSD11B1 | |
| SCHEMBL9844072 | 0.81 | GRM2 (0.53) | GRM2MAOAMAOBHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |