Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 11/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677231 | 0.91 | GRM2 (0.46) | GRM2SIGMAR1MAPK1HTR2AHTR2C | |
| SCHEMBL9844097 | 0.89 | GRM2 (0.55) | GRM2 | |
| SCHEMBL9844288 | 0.88 | GRM2 (0.53) | GRM2SIGMAR1 | |
| SCHEMBL9844243 | 0.86 | GRM2 (0.42) | GRM2SIGMAR1 | |
| SCHEMBL9844079 | 0.86 | GRM2 (0.60) | GRM2 | |
| SCHEMBL9844274 | 0.85 | GRM2 (0.53) | GRM2 | |
| SCHEMBL9844255 | 0.83 | GRM2 (0.52) | GRM2 | |
| SCHEMBL9844356 | 0.83 | GRM2 (0.52) | GRM2 | |
| SCHEMBL9844448 | 0.83 | ABCB1 (0.55) | GRM2 | |
| SCHEMBL9844309 | 0.82 | CARM1 (0.45) | GRM2SIGMAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |