Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PTAFR | P25105 | 1/20 | 0.52 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850494 | 0.90 | HRH1 (0.76) | HRH1LMNAL3MBTL1PTAFRSETD7 | |
| SCHEMBL8218752 | 0.89 | SETD7 (0.59) | HRH1LMNAL3MBTL1PTAFRSETD7 | |
| SCHEMBL9844364 | 0.88 | CHRM2 (0.57) | HRH1LMNAL3MBTL1PTAFRSETD7 | |
| SCHEMBL9718766 | 0.83 | HRH1 (0.61) | HRH1LMNAL3MBTL1PTAFRSETD7 | |
| SCHEMBL9844289 | 0.81 | FNTA (0.61) | HRH1LMNAL3MBTL1PTAFRSETD7 | |
| SCHEMBL3694376 | 0.80 | HRH1 (0.65) | HRH1LMNAPTAFRSETD7SMN1; SMN2 | |
| SCHEMBL11600013 | 0.80 | HRH1 (0.49) | HRH1LMNAL3MBTL1PTAFRSETD7 | |
| SCHEMBL11284129 | 0.79 | L3MBTL1 (0.51) | HRH1LMNAL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL1295044 | 0.79 | ALDH1A1 (0.64) | HRH1LMNAL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL14267624 | 0.78 | HRH1 (0.52) | HRH1LMNASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | disclosed |
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | disclosed |