Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844357 | 0.84 | TNF (0.39) | CA1CA2CA12CA9CA5A | |
| SCHEMBL25353843 | 0.78 | CA12 (0.64) | CA1CA2CA12CA9CA5A | |
| SCHEMBL9843826 | 0.78 | TAAR1 (0.58) | TNFSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL34463098 | 0.78 | TAAR1 (0.58) | TNFSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL9844000 | 0.77 | SLC6A3 (0.42) | CA1CA2CA12CA9CA5A | |
| SCHEMBL3361287 | 0.74 | SLC6A2 (0.41) | TNFSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL5428834 | 0.74 | SLC6A2 (0.41) | TNFSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL29474958 | 0.74 | SLC6A2 (0.41) | TNFSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL28797165 | 0.74 | SLC6A2 (0.41) | TNFSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL11974049 | 0.74 | HTR1A (0.49) | TNFSLC6A2SLC6A4KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447645-A1 | Aralkylesulfonyl ureas | BAYER AG (DE) | 1991-09-25 | — | — | EP | disclosed |