Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15677610 | 0.75 | CARM1 (0.58) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL18200131 | 0.73 | CARM1 (0.49) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL13896891 | 0.72 | DRD2 (0.60) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL20328148 | 0.71 | CARM1 (0.70) | DRD2DRD3DRD4HRH3CARM1 | |
| SCHEMBL11290526 | 0.70 | GRIN2D (0.33) | — | |
| SCHEMBL28142218 | 0.69 | LTA4H (0.50) | DRD2DRD3DRD4SIGMAR1 | |
| SCHEMBL28142214 | 0.69 | LTA4H (0.50) | DRD2DRD3DRD4SIGMAR1 | |
| SCHEMBL10465528 | 0.68 | LTA4H (0.52) | DRD4SIGMAR1 | |
| SCHEMBL8349073 | 0.68 | USP2 (0.41) | DRD3HRH3SIGMAR1 | |
| SCHEMBL6184734 | 0.68 | GRIN1 (0.40) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415030-A2 | 1-Substituted-1,2-dihydro-4-[(substituted)-phenyl]imidazo-[1,5-A]pyrimidine-8-carbonitriles | AMERICAN CYANAMID COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |