Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844107 | 0.76 | ALDH1A1 (0.53) | HSD11B1KDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL9844257 | 0.75 | HSD11B1 (0.47) | HSD11B1KDM4EKMT2AALDH1A1NPC1 | |
| SCHEMBL10574515 | 0.75 | USP7 (0.41) | HSD11B1USP7KMT2ANR1H2NR1H3 | |
| SCHEMBL18294597 | 0.74 | NR1H3 (0.51) | HSD11B1USP7KDM4EKMT2ANR1H2 | |
| SCHEMBL29565569 | 0.74 | AURKA (0.40) | HSD11B1USP7KMT2AALDH1A1POLB | |
| SCHEMBL9844367 | 0.73 | KDM4E (0.50) | HSD11B1USP7KDM4EKMT2AALDH1A1 | |
| SCHEMBL30655826 | 0.73 | KDM4E (0.46) | HSD11B1USP7KDM4EKMT2ANR1H2 | |
| SCHEMBL30136227 | 0.71 | GRM2 (0.44) | HSD11B1USP7KMT2ANR1H2NR1H3 | |
| SCHEMBL15716713 | 0.71 | KDM4E (0.62) | USP7KDM4ENR1H2NR1H3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL18128828 | 0.70 | KDM4E (0.61) | USP7KDM4ENR1H2NR1H3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441718-A1 | Herbicidally active triazolopyridine compounds | RHONE-POULENC AGROCHIMIE (FR) | 1991-08-14 | — | — | EP | disclosed |