Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14838661 | 0.68 | GRM2 (0.32) | — | |
| SCHEMBL27356095 | 0.68 | CYP2B6 (0.41) | CYP2B6CYP11B1CYP11B2KCNN4 | |
| SCHEMBL9650536 | 0.68 | CYP2B6 (0.46) | CYP2B6CYP11B1CYP11B2KCNN4 | |
| SCHEMBL1528523 | 0.68 | CYP2B6 (0.36) | CYP2B6CYP11B1CYP11B2 | |
| SCHEMBL5457963 | 0.67 | LMNA (0.42) | — | |
| SCHEMBL3744280 | 0.67 | CYP2B6 (0.38) | CYP2B6CYP11B1CYP11B2KCNN4 | |
| SCHEMBL4400626 | 0.66 | CYP2B6 (0.42) | CYP2B6CYP11B1CYP11B2 | |
| SCHEMBL2392136 | 0.65 | CYP2B6 (0.59) | CYP2B6CYP11B1CYP11B2KCNN4 | |
| SCHEMBL27753492 | 0.65 | CYP2B6 (0.54) | CYP2B6CYP11B1CYP11B2KCNN4 | |
| SCHEMBL13028023 | 0.64 | KCNH2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429304-A2 | Pyridone-carboxylic acid derivatives and their use as veterinary medicines | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-05-29 | — | — | EP | disclosed |
| US-5017708-A | Azabicycloalkanes | SHIONOGI & CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0359172-A1 | Azabicycloalkanes | SHIONOGI & CO., LTD. (JP) | 1990-03-21 | — | — | EP | disclosed |