Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844716 | 1.00 | ACHE (0.64) | ACHEBACE1 | |
| SCHEMBL9259329 | 0.87 | ACHE (0.64) | ACHEBACE1 | |
| SCHEMBL9259337 | 0.87 | ACHE (0.64) | ACHEBACE1 | |
| SCHEMBL9255759 | 0.85 | ACHE (0.64) | ACHEBACE1 | |
| SCHEMBL9255768 | 0.85 | ACHE (0.64) | ACHEBACE1 | |
| SCHEMBL9261584 | 0.83 | ACHE (0.54) | ACHEBACE1 | |
| SCHEMBL9261580 | 0.83 | ACHE (0.54) | ACHEBACE1 | |
| SCHEMBL9844701 | 0.81 | ACHE (0.65) | ACHEBACE1 | |
| SCHEMBL9844715 | 0.81 | ACHE (0.65) | ACHEBACE1 | |
| SCHEMBL9844698 | 0.81 | ACHE (0.65) | ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441517-A2 | Tricyclic amines as novel cholinesterase inhibitors | PFIZER INC. (US) | 1991-08-14 | — | — | EP | claimed |
| EP-0441517-A2 | Tricyclic amines as novel cholinesterase inhibitors | PFIZER INC. (US) | 1991-08-14 | — | — | EP | disclosed |