Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807992 | 0.97 | KDM4E (0.46) | KDM4ECYP3A4SMN1; SMN2TSHRDHODH | |
| SCHEMBL890399 | 0.92 | CYP3A4 (0.44) | KDM4ECYP3A4SMN1; SMN2TSHRDHODH | |
| Hydrochloric Acid SCHEMBL9563848 | 0.89 | CYP3A4 (0.43) | KDM4ECYP3A4SMN1; SMN2TSHRDHODH | |
| SCHEMBL3661752 | 0.87 | DHODH (0.57) | KDM4ECYP3A4SMN1; SMN2TSHRDHODH | |
| SCHEMBL4730653 | 0.85 | FURIN (0.45) | KDM4ECYP3A4SMN1; SMN2TSHRDHODH | |
| Ammonia Solution, Strong SCHEMBL20551039 | 0.85 | DHODH (0.55) | KDM4ECYP3A4SMN1; SMN2TSHRDHODH | |
| SCHEMBL813450 | 0.85 | PARP1 (0.53) | CYP3A4SMN1; SMN2TSHRDHODHPARP1 | |
| SCHEMBL6093183 | 0.82 | CYP3A4 (0.39) | KDM4ECYP3A4SMN1; SMN2TSHRDHODH | |
| SCHEMBL6093788 | 0.82 | CYP3A4 (0.39) | KDM4ECYP3A4SMN1; SMN2TSHRDHODH | |
| SCHEMBL6093793 | 0.82 | PARP1 (0.50) | KDM4ECYP3A4SMN1; SMN2TSHRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406992-A2 | New non-ionic carboxamide contrast agent | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | disclosed |