Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DDO | Q99489 | 1/20 | 0.48 |
| ▸ | TPMT | P51580 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL20551039 | 0.98 | DHODH (0.55) | DHODHKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL1498158 | 0.90 | DHODH (0.65) | DHODHKDM4EALDH1A1LMNATPMT | |
| SCHEMBL8366010 | 0.90 | DHODH (0.65) | DHODHKDM4EALDH1A1LMNATPMT | |
| SCHEMBL1807992 | 0.90 | KDM4E (0.46) | DHODHKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL2820215 | 0.90 | KDM4E (0.56) | DHODHKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL223304 | 0.90 | KDM4E (0.56) | DHODHKDM4EALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL8653192 | 0.87 | KDM4E (0.54) | DHODHKDM4EALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL9311860 | 0.87 | KDM4E (0.54) | DHODHKDM4EALDH1A1LMNAMEN1 | |
| Water SCHEMBL17938300 | 0.87 | KDM4E (0.54) | DHODHKDM4EALDH1A1LMNAMEN1 | |
| Iodide SCHEMBL9844728 | 0.87 | KDM4E (0.45) | DHODHKDM4EALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152854-C | Preparation of tri-iodo benzene compound | ��Īɳķ������˾ | 2004-06-09 | — | — | CN | claimed |
| US-20220048852-A1 | PROCESS OF PREPARING IOSIMENOL | OTSUKA PHARMA CO LTD (JP) | 2022-02-17 | — | — | US | disclosed |
| US-20200095191-A1 | PROCESS OF PREPARING IOSIMENOL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-03-26 | — | — | US | disclosed |
| EP-3619192-A1 | PROCESS OF PREPARING IOSIMENOL | Otsuka Pharmaceutical Co., Ltd. (JP) | 2020-03-11 | — | — | EP | disclosed |
| EP-3619192-A1 | PROCESS OF PREPARING IOSIMENOL | Otsuka Pharmaceutical Co., Ltd. (JP) | 2020-03-11 | — | — | EP | disclosed |
| WO-2018203525-A1 | PROCESS OF PREPARING IOSIMENOL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-11-08 | — | — | WO | disclosed |
| WO-2018203525-A1 | PROCESS OF PREPARING IOSIMENOL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-11-08 | — | — | WO | disclosed |
| US-8680334-B2 | Process for the preparation of iosimenol | MALLINCKRODT LLC (US) | 2014-03-25 | — | — | US | disclosed |
| US-20130261338-A1 | Process for the Preparation of Iosimenol | MALLINCKRODT LLC (US) | 2013-10-03 | — | — | US | disclosed |
| US-8445725-B2 | Process for the preparation of iosimenol | MALLINCKRODT LLC (US) | 2013-05-21 | — | — | US | disclosed |
| WO-2009091758-A1 | PROCESS FOR THE PREPARATION OF IOSIMENOL | MALLINCKRODT INC. (US) | 2009-07-23 | — | — | WO | disclosed |
| EP-1186305-A1 | New brominated compounds as contrast media for X-ray mammography | Schering Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |
| EP-0426610-B1 | Nonionic X-ray contrast agent with high iodine content | SCHERING AG (DE) | 1994-07-27 | — | — | EP | disclosed |
| EP-0460083-B1 | DERIVATIVES OF N-PHENYLBENZAMIDE WITH ANTI-ULCER AND ANTI-ALLERGY ACTIVITY AND A METHOD FOR THEIR PREPARATION | ROTTA RESEARCH LAB (IT) | 1994-06-08 | — | — | EP | disclosed |
| US-5232937-A | Cytoprotective agents, antisecretory agents, antagonist | ROTTA RESEARCH LABORATORIUM SPA. (IT) | 1993-08-03 | — | — | US | disclosed |
| EP-0460083-A1 | DERIVATIVES OF N-PHENYLBENZAMIDE WITH ANTI-ULCER AND ANTI-ALLERGY ACTIVITY AND A METHOD FOR THEIR PREPARATION. | ROTTA RESEARCH LAB (IT) | 1991-12-11 | — | — | EP | disclosed |
| EP-0426610-A2 | Nonionic X-ray contrast agent with high iodine content | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-05-08 | — | — | EP | disclosed |
| WO-1990009989-A1 | DERIVATIVES OF N-PHENYLBENZAMIDE WITH ANTI-ULCER AND ANTI-ALLERGY ACTIVITY AND A METHOD FOR THEIR PREPARATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1990-09-07 | — | — | WO | disclosed |
| EP-0015867-B1 | DIAMIDES OF TRIIODO-ISOPHTHALIC ACIDS, THEIR PREPARATION AND X-RAY CONTRAST AGENTS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-05-19 | — | — | EP | disclosed |
| EP-0015867-A1 | Diamides of triiodo-isophthalic acids, their preparation and X-ray contrast agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200095191-A1 | PROCESS OF PREPARING IOSIMENOL | AOC2, SSTR5, SSTR2 | DHODH 292/4885KDM4E 1491/4885ALDH1A1 3718/4885 |
| US-20220048852-A1 | PROCESS OF PREPARING IOSIMENOL | AOC2, SSTR2, NISCH | DHODH 420/4885KDM4E 2154/4885ALDH1A1 4215/4885 |
| US-20130261338-A1 | Process for the Preparation of Iosimenol | ITPR3, ITPR2, DHCR24 | DHODH 398/4885KDM4E 1832/4885ALDH1A1 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.