Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | FURIN | P09958 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9844728 | 0.97 | KDM4E (0.45) | KDM4ECYP3A4SMN1; SMN2PARP1TSHR | |
| SCHEMBL890399 | 0.94 | CYP3A4 (0.44) | KDM4ECYP3A4SMN1; SMN2PARP1TSHR | |
| Hydrochloric Acid SCHEMBL9563848 | 0.92 | CYP3A4 (0.43) | KDM4ECYP3A4SMN1; SMN2PARP1TSHR | |
| SCHEMBL3661752 | 0.90 | DHODH (0.57) | KDM4ECYP3A4SMN1; SMN2PARP1TSHR | |
| SCHEMBL4730653 | 0.88 | FURIN (0.45) | KDM4ECYP3A4SMN1; SMN2PARP1TSHR | |
| Ammonia Solution, Strong SCHEMBL20551039 | 0.88 | DHODH (0.55) | KDM4ECYP3A4SMN1; SMN2PARP1TSHR | |
| SCHEMBL813450 | 0.87 | PARP1 (0.53) | CYP3A4SMN1; SMN2PARP1TSHRPOLB | |
| SCHEMBL6093183 | 0.85 | CYP3A4 (0.39) | KDM4ECYP3A4SMN1; SMN2PARP1TSHR | |
| SCHEMBL6093788 | 0.85 | CYP3A4 (0.39) | KDM4ECYP3A4SMN1; SMN2PARP1TSHR | |
| SCHEMBL6093793 | 0.85 | PARP1 (0.50) | KDM4ECYP3A4SMN1; SMN2PARP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006486-B2 | Synthesis of N1,N3-bis(2,3-dihydroxypropyl)-5-nitroisophthalamide | LIEBEL-FLARSHEIM COMPANY LLC (US) | 2015-04-14 | — | — | US | claimed |
| EP-0484328-B1 | PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODO-5-AMINO-ISOPHTHALAMIDE COMPOUNDS | MALLINCKRODT INC (US) | 1995-06-14 | — | — | EP | claimed |
| EP-0484328-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODO-5-AMINO-N-ALKYLISOPHTHALAMIC ACID AND 2,4,6-TRIIODO-5-AMINO-ISOPHTHALAMIDE COMPOUNDS. | MALLINCKRODT INC (US) | 1992-05-13 | — | — | EP | claimed |
| US-5013865-A | X-ray contrast media, controlled stoichiometry and kinetics | MALLINCKRODT, INC. (US) | 1991-05-07 | — | — | US | claimed |
| WO-1991001296-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODO-5-AMINO-N-ALKYLISOPHTHALAMIC ACID AND 2,4,6-TRIIODO-5-AMINO-ISOPHTHALAMIDE COMPOUNDS | MALLINCKRODT, INC. (US) | 1991-02-07 | — | — | WO | claimed |
| US-4288362-A | Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | claimed |
| EP-3985001-B1 | PHARMACEUTICAL COMPOSITION FOR USE IN TREATING A CANCER | SERVIER LAB (FR) | 2026-04-29 | — | — | EP | disclosed |
| CN-119731169-A | Sodium channel regulator and application thereof | 上海汇伦医药股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-118043916-A | Insulated wire, wire harness, and method for manufacturing insulated wire | 株式会社自动网络技术研究所 | 2024-05-14 | — | — | CN | disclosed |
| WO-2024046253-A1 | SODIUM CHANNEL REGULATOR AND USE THEREOF | 上海汇伦医药股份有限公司 | 2024-03-07 | — | — | WO | disclosed |
| US-20240059733-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | SERVIER PHARMACEUTICALS LLC (US) | 2024-02-22 | — | — | US | disclosed |
| US-20230250050-A1 | PROCESS FOR THE PREPARATION OF IOPAMIDOL | GE HEALTHCARE AS (NO) | 2023-08-10 | — | — | US | disclosed |
| US-11667673-B2 | Therapeutically active compounds and their methods of use | SERVIER PHARMACEUTICALS LLC (US) | 2023-06-06 | — | — | US | disclosed |
| US-4288362-A | Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | disclosed |
| US-4260540-A | SPIN DYEING POLYACRYLONITRILE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4246401-A | Axomethine pigments | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |
| US-4225489-A | Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4154577-A | Uniformly disperse dyed water-swellable cellulosic fibers | BASF AKTIENGESELLSCHAFT (DE) | 1979-05-15 | — | — | US | disclosed |
| US-4083686-A | AZO DYES, WASHFASTNESS, PHOTOSTABILITY, SOLVENT RESISTANCE | BASF AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-4014863-A | LACQUERS, PRINTING INKS, PAINTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250050-A1 | PROCESS FOR THE PREPARATION OF IOPAMIDOL | APC, PKD1, ITPA | KDM4E 3866/4885CYP3A4 645/4885SMN1; SMN2 4044/4885 |
| US-20240059733-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | IDH1, IDH3B, IDH3A | KDM4E 446/4885CYP3A4 2656/4885SMN1; SMN2 261/4885 |
| US-11667673-B2 | Therapeutically active compounds and their methods of use | IDH1, IDH3B, IDH3A | KDM4E 446/4885CYP3A4 2656/4885SMN1; SMN2 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.