Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946466 | 0.82 | HPGD (0.49) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8946459 | 0.82 | HPGD (0.49) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8946463 | 0.82 | HPGD (0.49) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8946641 | 0.77 | HPGD (0.39) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8946633 | 0.77 | HPGD (0.39) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8946630 | 0.77 | HPGD (0.39) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8946338 | 0.75 | AURKA (0.41) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8946327 | 0.75 | AURKA (0.41) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8946332 | 0.75 | AURKA (0.41) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8946475 | 0.70 | CYP3A4 (0.46) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | disclosed |