Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLR1 | P15328 | 3/20 | 0.40 |
| ▸ | FOLR2 | P14207 | 2/20 | 0.40 |
| ▸ | GART | P22102 | 2/20 | 0.40 |
| ▸ | SLC46A1 | Q96NT5 | 2/20 | 0.40 |
| ▸ | SLC19A1 | P41440 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 7/20 | 0.38 |
| ▸ | FLT1 | P17948 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844981 | 0.81 | EGFR (0.46) | EGFRFLT1PDGFRBKDRALDH1A1 | |
| SCHEMBL9849678 | 0.79 | DAO (0.38) | FOLR1FOLR2GARTSLC19A1DAO | |
| SCHEMBL1603787 | 0.77 | GART (0.65) | FOLR1FOLR2GARTSLC46A1SLC19A1 | |
| SCHEMBL9850000 | 0.75 | FOLR2 (0.37) | FOLR1FOLR2GARTSLC46A1SLC19A1 | |
| SCHEMBL9850059 | 0.75 | FOLR2 (0.39) | FOLR1FOLR2GARTSLC46A1SLC19A1 | |
| SCHEMBL9849648 | 0.74 | FOLR2 (0.37) | FOLR1FOLR2GARTSLC46A1SLC19A1 | |
| SCHEMBL9844839 | 0.71 | EGFR (0.46) | EGFRFLT1PDGFRBALDH1A1 | |
| SCHEMBL9850003 | 0.70 | CYP4A11 (0.49) | DAOALDH1A1LMNAMAPT | |
| SCHEMBL8226496 | 0.68 | DAO (0.47) | DAOMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28342951 | 0.67 | DAO (0.44) | DAOALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |