Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844777 | 1.00 | MTNR1A (0.39) | MTNR1AMTNR1BCHRNB2CHRNA4TSHR | |
| SCHEMBL9844767 | 1.00 | MTNR1A (0.39) | MTNR1AMTNR1BCHRNB2CHRNA4TSHR | |
| SCHEMBL8946281 | 0.77 | HTR2A (0.39) | MEN1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL8946289 | 0.77 | HTR2A (0.39) | MEN1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL8946284 | 0.77 | HTR2A (0.39) | MEN1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL8946559 | 0.74 | MAPT (0.36) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL8946552 | 0.74 | MAPT (0.36) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL8946557 | 0.74 | MAPT (0.36) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL8946693 | 0.74 | ALDH1A1 (0.45) | MTNR1AMTNR1BCHRNB2CHRNA4MAPT | |
| SCHEMBL8946700 | 0.74 | ALDH1A1 (0.45) | MTNR1AMTNR1BCHRNB2CHRNA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | disclosed |