Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | GART | P22102 | 4/20 | 0.44 |
| ▸ | DHFR | P00374 | 3/20 | 0.44 |
| ▸ | FOLR1 | P15328 | 3/20 | 0.44 |
| ▸ | FOLR2 | P14207 | 2/20 | 0.44 |
| ▸ | SLC46A1 | Q96NT5 | 2/20 | 0.44 |
| ▸ | SLC19A1 | P41440 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | SCNN1A | P37088 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844839 | 0.93 | EGFR (0.46) | CYP4A11CYP4F2DHFRTP53TLR8 | |
| SCHEMBL9844981 | 0.83 | EGFR (0.46) | CYP4A11CYP4F2DHFRTP53TLR8 | |
| SCHEMBL9085311 | 0.76 | NAMPT (0.53) | CYP4A11CYP4F2DHFR | |
| SCHEMBL9889382 | 0.75 | DHFR (0.60) | DHFRTLR8TLR7 | |
| SCHEMBL9339199 | 0.75 | DHFR (0.54) | CYP4A11CYP4F2DHFRTP53TLR8 | |
| SCHEMBL9225900 | 0.74 | GART (0.73) | GARTDHFRFOLR1FOLR2SLC46A1 | |
| SCHEMBL9339245 | 0.73 | CYP4A11 (0.55) | CYP4A11CYP4F2DHFRTP53TLR8 | |
| SCHEMBL9341073 | 0.72 | CYP4A11 (0.53) | CYP4A11CYP4F2DHFRTP53TLR8 | |
| SCHEMBL12176878 | 0.72 | CYP4A11 (0.70) | CYP4A11CYP4F2TP53LOXL2GAA | |
| SCHEMBL18551757 | 0.70 | GART (0.65) | GARTDHFRFOLR1FOLR2SLC46A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |