SCHEMBL9845089

SCHEMBL9845089

CCC[C@H]1CC[C@H](c2ccccc2-c2ccccc2)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.43
PTGS2 P35354 1/20 0.42
KDM4E B2RXH2 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA1D P25100 1/20 0.38
ADRA1A P35348 1/20 0.38
OPRL1 P41146 2/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
PDK2 Q15119 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30475373 1.00 BRD4 (0.43) BRD4PTGS2KDM4ERAB9AL3MBTL1
SCHEMBL263138 1.00 BRD4 (0.43) BRD4PTGS2KDM4ERAB9AL3MBTL1
SCHEMBL7912542 0.91 GAA (0.43) BRD4PTGS2RAB9ACYP2C9MEN1
SCHEMBL262956 0.91 GAA (0.43) BRD4PTGS2RAB9ACYP2C9MEN1
SCHEMBL4650755 0.90 CYP2C9 (0.44) PTGS2KDM4ERAB9AL3MBTL1CYP2C9
SCHEMBL9639405 0.90 CYP2C9 (0.44) PTGS2KDM4ERAB9AL3MBTL1CYP2C9
SCHEMBL262121 0.89 GAA (0.41) BRD4PTGS2RAB9ACYP2C9MEN1
SCHEMBL9751895 0.89 GAA (0.41) BRD4PTGS2RAB9ACYP2C9MEN1
SCHEMBL29906122 0.89 GAA (0.41) BRD4PTGS2RAB9ACYP2C9MEN1
SCHEMBL4650756 0.88 CHRNB2 (0.48) BRD4KDM4ERAB9AL3MBTL1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118235072-A Optical film and polarizing plate 东曹株式会社 2024-06-21 CN disclosed
CN-109601014-B Electrical control device with variable scattering by liquid crystals 法国圣戈班玻璃厂 2022-07-08 CN disclosed
CN-109154734-B Low haze switchable liquid crystal arrangement for switchable windows or the like 佳殿玻璃有限公司 2021-11-19 CN disclosed
EP-3662322-A1 ELECTRICALLY CONTROLLABLE DEVICE WITH VARIABLE DIFFUSION BY LIQUID CRYSTALS SAINT-GOBAIN GLASS FRANCE (FR) 2020-06-10 EP disclosed
EP-3658980-A1 VEHICLE WINDOW PANE HAVING PDLC FILM WITH A DEFINED DROPLET SIZE DISTRIBUTION FOR REDUCING THE CORONA EFFECT Saint-Gobain Glass France (FR) 2020-06-03 EP disclosed
CN-109154734-A Low haze switchable liquid crystal for switchable glazings or the like is arranged 佳殿玻璃有限公司 2019-01-04 CN disclosed
US-9791759-B2 Multiple glazing with variable scattering by liquid crystals and its method of manufacture CARDINAL IG COMPANY (US) 2017-10-17 US disclosed
CN-103154807-B There is double glazing goods and the manufacture method thereof of the variable scattering that liquid crystal realizes SAINT-GOBAIN GLASS FRANCE (FR) 2016-01-20 CN disclosed
US-20150098037-A1 MULTIPLE GLAZING WITH VARIABLE SCATTERING BY LIQUID CRYSTALS AND ITS METHOD OF MANUFACTURE SAINT-GOBAIN GLASS FRANCE (FR) 2015-04-09 US disclosed
CN-104380184-A Method for producing a multiple glazing unit with variable diffusion by PDLC layer and a multiple glazing unit with a PDLC layer produced according to said method SAINT GOBAIN 2015-02-25 CN disclosed
CN-104246585-A Multiple glazing with variable diffusion by liquid crystals SAINT GOBAIN 2014-12-24 CN disclosed
CN-104106000-A Multiple glazing with variable diffusion through liquid crystals and method for making same SAINT GOBAIN 2014-10-15 CN disclosed
CN-103238102-A Multiple glazing having variable diffusion by liquid crystals, and method for manufacturing same SAINT GOBAIN 2013-08-07 CN disclosed
EP-0414048-A2 Matrix-liquid crystal display MERCK PATENT GmbH (DE) 1991-02-27 EP disclosed
EP-0365962-A1 Matrix-type liquid-crystal display MERCK PATENT GmbH (DE) 1990-05-02 EP disclosed
EP-0226592-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1989-09-06 EP disclosed