SCHEMBL4650756

SCHEMBL4650756

CCCC1CCC(c2cccc(-c3ccccc3)c2C2CCC(CCC)CC2)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.48
CHRNA4 P43681 1/20 0.48
KDM4E B2RXH2 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP2C9 P11712 1/20 0.37
PDK2 Q15119 1/20 0.36
PDK4 Q16654 1/20 0.36
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPK1 P28482 2/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HTR1A P08908 2/20 0.35
HTR7 P34969 2/20 0.35
OPRL1 P41146 1/20 0.34
BRD4 O60885 1/20 0.34
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9639406 1.00 CHRNB2 (0.48) CHRNB2CHRNA4KDM4ERAB9AL3MBTL1
SCHEMBL4653175 0.94 CHRNB2 (0.43) CHRNB2CHRNA4KDM4ERAB9AL3MBTL1
SCHEMBL10882600 0.94 CHRNB2 (0.43) CHRNB2CHRNA4KDM4ERAB9AL3MBTL1
SCHEMBL8416017 0.91 CHRNB2 (0.45) CHRNB2CHRNA4RAB9ACYP2C9MEN1
SCHEMBL8416015 0.91 CHRNB2 (0.45) CHRNB2CHRNA4RAB9ACYP2C9MEN1
SCHEMBL263138 0.88 BRD4 (0.43) CHRNB2CHRNA4KDM4ERAB9AL3MBTL1
SCHEMBL30475373 0.88 BRD4 (0.43) CHRNB2CHRNA4KDM4ERAB9AL3MBTL1
SCHEMBL9845089 0.88 BRD4 (0.43) CHRNB2CHRNA4KDM4ERAB9AL3MBTL1
SCHEMBL4650921 0.85 OPRL1 (0.39) CHRNB2CHRNA4KDM4ERAB9AL3MBTL1
SCHEMBL9166203 0.85 KDM4E (0.36) CHRNB2CHRNA4KDM4ERAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599562-B9 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2008-09-24 EP claimed
EP-1599562-B1 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2007-05-16 EP claimed
CN-109601014-A With the electric control gear for the scattering that liquid crystal is changed can be passed through 法国圣戈班玻璃厂 2019-04-09 CN disclosed
CN-109588053-A For reducing the vehicle glazing panels comprising the PDLC film with specific droplet size distribution of corona effect 法国圣戈班玻璃厂 2019-04-05 CN disclosed
CN-103154807-B There is double glazing goods and the manufacture method thereof of the variable scattering that liquid crystal realizes SAINT-GOBAIN GLASS FRANCE (FR) 2016-01-20 CN disclosed
CN-104380184-A Method for producing a multiple glazing unit with variable diffusion by PDLC layer and a multiple glazing unit with a PDLC layer produced according to said method SAINT GOBAIN 2015-02-25 CN disclosed
EP-0491901-A1 ELECTRO-OPTICAL SYSTEM MERCK PATENT GmbH (DE) 1992-07-01 EP disclosed
WO-1992001240-A1 ELECTRO-OPTICAL SYSTEM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1992-01-23 WO disclosed