Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845131 | 0.97 | RECQL (0.52) | RECQLSIGMAR1MEN1KMT2APDE4B | |
| SCHEMBL9845125 | 0.96 | RECQL (0.51) | RECQLSIGMAR1MEN1KMT2APDE4B | |
| SCHEMBL9845132 | 0.94 | SIGMAR1 (0.49) | RECQLSIGMAR1MEN1KMT2APDE4B | |
| SCHEMBL9845096 | 0.90 | RECQL (0.50) | RECQLMEN1KMT2APDE4BLMNA | |
| SCHEMBL9845100 | 0.87 | RECQL (0.53) | RECQLMEN1KMT2APDE4BLMNA | |
| SCHEMBL9845120 | 0.86 | RECQL (0.52) | RECQLMEN1KMT2APDE4BLMNA | |
| SCHEMBL9845110 | 0.84 | RECQL (0.46) | RECQLSIGMAR1MEN1KMT2APDE4B | |
| SCHEMBL9845099 | 0.82 | RECQL (0.47) | RECQLMEN1KMT2APDE4BLMNA | |
| SCHEMBL9845092 | 0.78 | RECQL (0.49) | RECQLMEN1KMT2APDE4BLMNA | |
| SCHEMBL9845130 | 0.77 | RECQL (0.45) | RECQLMEN1KMT2APDE4BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431942-A2 | Percutaneously absorbable pharmaceutical preparation containing dopamine derivative | SANSHO CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |