Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845099 | 0.96 | RECQL (0.47) | RECQLPDE4BLMNAPOLBATM | |
| SCHEMBL9845092 | 0.94 | RECQL (0.49) | RECQLPDE4BLMNAHDAC1HDAC2 | |
| SCHEMBL9845110 | 0.81 | RECQL (0.46) | RECQLPDE4BLMNAPOLBATM | |
| SCHEMBL9845132 | 0.79 | SIGMAR1 (0.49) | RECQLPDE4BLMNAPOLBATM | |
| SCHEMBL9845100 | 0.78 | RECQL (0.53) | RECQLPDE4BLMNAHDAC1HDAC2 | |
| SCHEMBL9845096 | 0.78 | RECQL (0.50) | RECQLPDE4BLMNAPOLBATM | |
| SCHEMBL9845102 | 0.77 | RECQL (0.49) | RECQLPDE4BLMNAPOLBATM | |
| SCHEMBL9845131 | 0.77 | RECQL (0.52) | RECQLPDE4BLMNAHDAC1HDAC2 | |
| SCHEMBL9845120 | 0.77 | RECQL (0.52) | RECQLPDE4BLMNAHDAC1HDAC2 | |
| SCHEMBL1969068 | 0.76 | ATM (0.67) | LMNAPOLBATMKCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431942-A2 | Percutaneously absorbable pharmaceutical preparation containing dopamine derivative | SANSHO CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |