Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14736855 | 1.00 | CYP3A4 (0.36) | CYP3A4HTTSMN1; SMN2SMYD2KMT2A | |
| SCHEMBL12587456 | 0.85 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2KMT2A | |
| SCHEMBL16350794 | 0.85 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2KMT2A | |
| SCHEMBL12772162 | 0.85 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2KMT2A | |
| SCHEMBL14457866 | 0.83 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2KMT2A | |
| SCHEMBL13577566 | 0.81 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL25591750 | 0.80 | HCAR2 (0.41) | CYP3A4HTTSMN1; SMN2TAAR1 | |
| SCHEMBL705925 | 0.80 | RIPK1 (0.34) | CYP3A4HTTSMN1; SMN2SMYD2KMT2A | |
| SCHEMBL5546414 | 0.80 | KMT2A (0.36) | KMT2AMEN1TAAR1 | |
| SCHEMBL12770239 | 0.79 | NR1H2 (0.32) | CYP3A4HTTSMN1; SMN2SMYD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206567-B | Preparation method of fused ring compound | 天津辰欣药物研究有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-118206567-A | Preparation method of fused ring compound | 天津辰欣药物研究有限公司 | 2024-06-18 | — | — | CN | disclosed |
| EP-0462667-A2 | Beta-lactams as antihypercholesterolemics | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |