Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845206 | 0.80 | CYP3A4 (0.36) | KMT2AMEN1TAAR1 | |
| SCHEMBL14736855 | 0.80 | CYP3A4 (0.36) | KMT2AMEN1TAAR1 | |
| SCHEMBL106923 | 0.78 | TDP1 (0.37) | TAAR1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL393947 | 0.72 | TDP1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL11130173 | 0.72 | TDP1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL11526330 | 0.72 | ADRA2A (0.40) | TAAR1ALDH1A1TDP1HCAR2 | |
| SCHEMBL645558 | 0.71 | ALDH1A1 (0.35) | ALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL7737248 | 0.70 | ESR1 (0.31) | — | |
| SCHEMBL3276265 | 0.70 | ALDH1A3 (0.42) | KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL94527 | 0.70 | ALDH1A3 (0.42) | KMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519993-B1 | ROOM TEMPERATURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | AMBER CHEMICAL COMPANY LTD (GB) | 2007-04-18 | — | — | EP | claimed |