SCHEMBL9845248

SCHEMBL9845248

COc1ccc(COCc2ccc(OC)c(-c3ccccc3)c2Cl)c(Cl)c1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.39
FABP4 P15090 2/20 0.38
FABP3 P05413 1/20 0.38
FABP5 Q01469 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 5/20 0.37
KDM4E B2RXH2 4/20 0.37
S1PR4 O95977 1/20 0.37
HSP90AA1 P07900 1/20 0.37
G6PD P11413 1/20 0.37
S1PR1 P21453 1/20 0.37
MAPK1 P28482 1/20 0.37
OPRK1 P41145 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
MCL1 Q07820 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2490409 0.74 CD274 (0.38) FABP4FABP3FABP5KDM4EALDH1A1
SCHEMBL2490820 0.74 TAAR1 (0.39) MAPK1RAB9AIDO1
SCHEMBL2490787 0.71 KDM4E (0.45) FABP4FABP3FABP5MEN1KMT2A
SCHEMBL9706208 0.71 FABP3 (0.40) FABP4FABP3FABP5MEN1KMT2A
SCHEMBL30884236 0.69 PDE4B (0.47) FABP4FABP3FABP5MEN1KMT2A
SCHEMBL26259629 0.69 MAPT (0.52) FABP4FABP3FABP5MEN1KMT2A
SCHEMBL355567 0.68 CA1 (0.57) ARFABP4FABP3FABP5MEN1
SCHEMBL27614464 0.68 HTR2A (0.43) FABP4FABP3FABP5MEN1KMT2A
SCHEMBL16109256 0.67 PDE4B (0.53) FABP4FABP3FABP5MEN1KMT2A
SCHEMBL12994038 0.67 ALDH1A1 (0.45) FABP4FABP3FABP5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0408339-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-16 EP disclosed