Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | AGER | Q15109 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965011 | 0.80 | ALDH1A1 (0.46) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL10528638 | 0.80 | HSD17B10 (0.49) | AHCYADORA2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL965012 | 0.80 | ALDH1A1 (0.32) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9019773 | 0.76 | PDE3A (0.39) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9019861 | 0.75 | ALDH1A1 (0.34) | ADORA2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9019755 | 0.73 | ALDH1A1 (0.32) | ADORA2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9019779 | 0.73 | CYP3A4 (0.40) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27658628 | 0.73 | ADORA2A (0.41) | ADORA2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL10404957 | 0.72 | CCNE1 (0.52) | PIK3CGAHCYADORA2AHSD17B10ALDH1A1 | |
| SCHEMBL9019744 | 0.72 | ALDH1A1 (0.32) | HSD17B10KDM4EALDH1A1HPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |
| CN-1054982-A | The purine that replaces, its preparation method and as the purposes of antiviral drug | HOECHST AG (DE) | 1991-10-02 | — | — | CN | disclosed |