SCHEMBL965012

SCHEMBL965012

Nc1ncc2c(ncn2COC(O)CCO)n1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
ADRA1A P35348 1/20 0.32
HSD17B10 Q99714 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
NFKB1 P19838 1/20 0.32
BLM P54132 1/20 0.32
VCP P55072 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL965011 0.83 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDADRA1AHSD17B10
SCHEMBL9845285 0.80 PIK3CG (0.33) ALDH1A1KDM4EHPGDADRA1AHSD17B10
SCHEMBL9124435 0.79
SCHEMBL9019861 0.78 ALDH1A1 (0.34) ALDH1A1KDM4EHPGDADRA1AHSD17B10
SCHEMBL9019773 0.76 PDE3A (0.39) ALDH1A1KDM4EHPGDADRA1AHSD17B10
SCHEMBL8960765 0.76 ELANE (0.32) ALDH1A1KDM4EHPGDADRA1AHSD17B10
SCHEMBL9845287 0.75 KDM4E (0.31) ALDH1A1KDM4EHPGDADRA1AHSD17B10
SCHEMBL9019744 0.74 ALDH1A1 (0.32) ALDH1A1KDM4EHPGDADRA1AHSD17B10
SCHEMBL9019755 0.73 ALDH1A1 (0.32) ALDH1A1KDM4EHPGDADRA1AHSD17B10
SCHEMBL8210030 0.73 ALDH1A1 (0.48) ALDH1A1KDM4EHPGDADRA1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160346287-A1 METHOD OF TREATING VIRAL INFECTIONS EPIPHANY BIOSCIENCES, INC. 2016-12-01 US claimed
US-20150050241-A1 METHOD OF TREATING VIRAL INFECTIONS EPIPHANY BIOSCIENCES, INC. 2015-02-19 US claimed
US-20250339502-A1 RIBONUCLEASES FOR TREATING VIRAL INFECTIONS ORGENESIS INC. (US) 2025-11-06 US disclosed
US-20230147602-A1 RIBONUCLEASES FOR TREATING VIRAL INFECTIONS ORGENESIS INC. (US) 2023-05-11 US disclosed
WO-2021188866-A1 RIBONUCLEASES FOR TREATING VIRAL INFECTIONS ORGENESIS INC. (US) 2021-09-23 WO disclosed
WO-2021188974-A1 RIBONUCLEASES FOR TREATING VIRAL INFECTIONS ORGENESIS INC. (US) 2021-09-23 WO disclosed
US-20160346287-A1 METHOD OF TREATING VIRAL INFECTIONS EPIPHANY BIOSCIENCES, INC. 2016-12-01 US disclosed
US-20150094327-A1 COMPOSITIONS AND METHODS FOR INHIBITING RESOLVASES NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR 2015-04-02 US disclosed
EP-2842559-A2 Compounds, compositions and methods for the treatment of viral infections and other medical disorders Chimerix, Inc. (US) 2015-03-04 EP disclosed
US-20150050241-A1 METHOD OF TREATING VIRAL INFECTIONS EPIPHANY BIOSCIENCES, INC. 2015-02-19 US disclosed
EP-1868628-B1 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF POXVIRUS INFECTIONS CHIMERIX INC (US) 2014-06-11 EP disclosed
EP-1865967-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER MEDICAL DISORDERS Chimerix, Inc. (US) 2007-12-19 EP disclosed
WO-2007047339-A2 METHODS OF INHIBITING POXVIRUS GROWTH THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2007-04-26 WO disclosed
WO-2006110656-A9 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER MEDICAL DISORDERS CHIMERIX INC (US) 2007-03-01 WO disclosed
US-20070003608-A1 Compounds, compositions and methods for the treatment of viral infections and other medical disorders CHIMERIX, INC. 2007-01-04 US disclosed
US-20070003516-A1 Compounds, compositions and methods for the treatment of poxvirus infections EMERGENT BIODEFENSE OPERATIONS LANSING LLC 2007-01-04 US disclosed
WO-2006110656-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER MEDICAL DISORDERS CHIMERIX, INC. (US) 2006-10-19 WO disclosed
WO-2006110655-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF POXVIRUS INFECTIONS CHIMERIX, INC. (US) 2006-10-19 WO disclosed
CN-1077454-A 2-amino-7- [ (1, 3-dihydroxy-2-propoxy) methyl ] purine carboxylate, its preparation and use HOECHST AG (DE) 1993-10-20 CN disclosed
US-5225550-A PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160346287-A1 METHOD OF TREATING VIRAL INFECTIONS IFNG, BCL9, GDA ALDH1A1 3739/4885KDM4E 2446/4885HPGD 632/4885
US-20070003516-A1 Compounds, compositions and methods for the treatment of poxvirus infections IFNG, POLI, STING1 ALDH1A1 3014/4885KDM4E 2143/4885HPGD 873/4885
US-20150050241-A1 METHOD OF TREATING VIRAL INFECTIONS IFNG, BCL9, GDA ALDH1A1 3739/4885KDM4E 2446/4885HPGD 632/4885
US-20070003608-A1 Compounds, compositions and methods for the treatment of viral infections and other medical disorders ACE, CYP27A1, LIPC ALDH1A1 857/4885KDM4E 989/4885HPGD 729/4885
US-20150094327-A1 COMPOSITIONS AND METHODS FOR INHIBITING RESOLVASES FEN1, RCE1, APEX1 ALDH1A1 4188/4885KDM4E 1800/4885HPGD 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.