Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575551 | 0.84 | KDM4E (0.30) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9019744 | 0.83 | ALDH1A1 (0.32) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9019773 | 0.79 | PDE3A (0.39) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9019861 | 0.79 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL965011 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9019755 | 0.77 | ALDH1A1 (0.32) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL965012 | 0.75 | ALDH1A1 (0.32) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8210030 | 0.74 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8205815 | 0.72 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8777016 | 0.72 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |
| CN-1054982-A | The purine that replaces, its preparation method and as the purposes of antiviral drug | HOECHST AG (DE) | 1991-10-02 | — | — | CN | disclosed |