Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222080 | 0.90 | KMO (0.73) | KMOALDH1A1GAAKDM4ETSHR | |
| SCHEMBL10533924 | 0.86 | TSHR (0.60) | KMOCHRM5CHRM1CHRM3ALDH1A1 | |
| SCHEMBL10619000 | 0.82 | CHRM1 (0.64) | KMOCHRM5CHRM1CHRM3ALDH1A1 | |
| SCHEMBL30096013 | 0.81 | ALDH1A1 (0.68) | KMOALDH1A1GAAKDM4ETSHR | |
| SCHEMBL4971763 | 0.81 | ALDH1A1 (0.68) | KMOALDH1A1GAAKDM4ETSHR | |
| SCHEMBL4052306 | 0.80 | CHRM1 (0.58) | KMOCHRM5CHRM1CHRM3ALDH1A1 | |
| SCHEMBL10530276 | 0.80 | ALDH1A1 (0.52) | CHRM5CHRM1CHRM3ALDH1A1GAA | |
| SCHEMBL10532024 | 0.80 | ALDH1A1 (0.52) | CHRM5CHRM1CHRM3ALDH1A1GAA | |
| SCHEMBL9275467 | 0.79 | CHRM5 (0.57) | CHRM5CHRM1CHRM3ALDH1A1GAA | |
| SCHEMBL19030483 | 0.77 | BRD4 (0.57) | CHRM5CHRM1CHRM3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406993-A2 | Substituted benzoxazolinone and benzoxazinone derivatives, process for their preparation and their use as agent with herbicide activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | disclosed |