Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909007 | 0.84 | NPC1 (0.39) | NPC1TTRCES1CYP11B1CYP11B2 | |
| SCHEMBL10908994 | 0.82 | KMT2A (0.39) | NPC1TTRCES1CYP11B1CYP11B2 | |
| SCHEMBL10994291 | 0.79 | NPC1 (0.36) | NPC1TTRCES1CYP11B1CYP11B2 | |
| SCHEMBL10912882 | 0.78 | MEN1 (0.43) | NPC1TTRCES1TDP1CYP11B1 | |
| SCHEMBL11714046 | 0.78 | NPC1 (0.57) | NPC1TTRTDP1MAPT | |
| SCHEMBL10909271 | 0.77 | CES1 (0.50) | CES1CYP11B1CYP11B2 | |
| SCHEMBL9845436 | 0.77 | CYP11B1 (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL9845452 | 0.75 | MEN1 (0.38) | CES1TDP1MAPT | |
| SCHEMBL9845456 | 0.70 | KDM4E (0.32) | MAPT | |
| SCHEMBL9845480 | 0.70 | NR3C2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406993-A2 | Substituted benzoxazolinone and benzoxazinone derivatives, process for their preparation and their use as agent with herbicide activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | disclosed |