Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845456 | 0.80 | KDM4E (0.32) | MEN1KMT2AHSD17B10LMNAALDH1A1 | |
| SCHEMBL9845449 | 0.78 | MEN1 (0.31) | MEN1KMT2ATSHR | |
| SCHEMBL9845446 | 0.77 | LMNA (0.36) | MEN1KMT2ATSHRHSD17B10LMNA | |
| SCHEMBL9845462 | 0.75 | NPC1 (0.38) | TDP1MAPTCES1 | |
| SCHEMBL10909007 | 0.74 | NPC1 (0.39) | MEN1KMT2ATSHRMAPTCES1 | |
| SCHEMBL10910976 | 0.72 | MEN1 (0.39) | MEN1KMT2ATSHRHSD17B10LMNA | |
| SCHEMBL10910689 | 0.72 | HTR2A (0.37) | MEN1KMT2ATSHRLMNAL3MBTL1 | |
| SCHEMBL10997214 | 0.72 | L3MBTL1 (0.33) | MEN1KMT2ATSHRLMNAL3MBTL1 | |
| SCHEMBL10995658 | 0.70 | LMNA (0.32) | MEN1KMT2ALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL10997207 | 0.70 | LMNA (0.37) | MEN1KMT2ALMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406993-A2 | Substituted benzoxazolinone and benzoxazinone derivatives, process for their preparation and their use as agent with herbicide activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | disclosed |