Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845462 | 0.84 | NPC1 (0.38) | NPC1TTRCES1CYP11B1CYP11B2 | |
| SCHEMBL10908994 | 0.84 | KMT2A (0.39) | NPC1TTRCES1KMT2AMEN1 | |
| SCHEMBL10994291 | 0.80 | NPC1 (0.36) | NPC1TTRCES1KMT2ACYP11B1 | |
| SCHEMBL10912882 | 0.79 | MEN1 (0.43) | NPC1TTRCES1KMT2AMEN1 | |
| SCHEMBL10909271 | 0.78 | CES1 (0.50) | CES1KMT2AMEN1CYP11B1CYP11B2 | |
| SCHEMBL9845452 | 0.74 | MEN1 (0.38) | CES1KMT2AMEN1TSHRMAPT | |
| SCHEMBL9845446 | 0.70 | LMNA (0.36) | CES1KMT2AMEN1TSHRHTT | |
| SCHEMBL11536660 | 0.68 | HTR1A (0.48) | CES1KMT2AMEN1CYP11B1CYP11B2 | |
| SCHEMBL2269084 | 0.67 | KMT2A (0.60) | NPC1CES1KMT2AMEN1MAPT | |
| SCHEMBL9845456 | 0.66 | KDM4E (0.32) | KMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103797-B1 | SUBSTITUTED BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 1986-11-26 | — | — | EP | disclosed |
| US-4537888-A | Substituted benzoxazine derivatives and fungicidal use | BAYER AKTIENGESELLSCHAFT (DE) | 1985-08-27 | — | — | US | disclosed |
| EP-0103797-A2 | Substituted benzoxazine derivatives | BAYER AG (DE) | 1984-03-28 | — | — | EP | disclosed |