Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761567 | 0.83 | NLRP3 (0.44) | ALDH1A1MEN1KMT2ANLRP3ANPEP | |
| SCHEMBL6544554 | 0.78 | ANPEP (0.47) | ALDH1A1MEN1KMT2ANLRP3ANPEP | |
| SCHEMBL9614032 | 0.78 | ANPEP (0.47) | ALDH1A1MEN1KMT2ANLRP3ANPEP | |
| SCHEMBL6901572 | 0.77 | TDP1 (0.44) | ALDH1A1MEN1KMT2ANLRP3ANPEP | |
| SCHEMBL9644400 | 0.75 | NLRP3 (0.39) | ALDH1A1MEN1KMT2ANLRP3ANPEP | |
| SCHEMBL8462752 | 0.75 | NLRP3 (0.39) | ALDH1A1MEN1KMT2ANLRP3ANPEP | |
| SCHEMBL11143197 | 0.75 | CACNA1C (0.43) | ALDH1A1MEN1KMT2ANLRP3ANPEP | |
| SCHEMBL3474559 | 0.75 | NLRP3 (0.52) | ALDH1A1MEN1KMT2ANLRP3ALOX15 | |
| SCHEMBL6902097 | 0.75 | ANPEP (0.52) | ALDH1A1MEN1KMT2ANLRP3ANPEP | |
| SCHEMBL10959622 | 0.74 | NLRP3 (0.58) | ALDH1A1NLRP3ANPEPCYP2C19ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422848-A1 | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0381330-A1 | Fungicides | ZENECA LIMITED (GB) | 1990-08-08 | — | — | EP | disclosed |