SCHEMBL9761567

SCHEMBL9761567

CCc1cccc(CC)c1NC(=O)C(Cl)COC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 2/20 0.44
ANPEP P15144 1/20 0.44
CYP2C19 P33261 2/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
HIF1A Q16665 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CACNA1C Q13936 2/20 0.41
SCN5A Q14524 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HTT P42858 3/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6901572 0.85 TDP1 (0.44) NLRP3ANPEPCYP2C19ALOX15TSHR
SCHEMBL9614047 0.84 LMNA (0.36) TDP1CACNA1CSCN5AALDH1A1KDM4E
SCHEMBL9845475 0.83 ALDH1A1 (0.41) NLRP3ANPEPCYP2C19ALOX15TSHR
SCHEMBL9614032 0.83 ANPEP (0.47) NLRP3ANPEPCYP2C19ALOX15TSHR
SCHEMBL6544554 0.83 ANPEP (0.47) NLRP3ANPEPCYP2C19ALOX15TSHR
SCHEMBL5087609 0.80 NR1I2 (0.43) NLRP3ANPEPCYP2C19ALOX15TSHR
SCHEMBL9644400 0.80 NLRP3 (0.39) NLRP3ANPEPCYP2C19ALOX15TSHR
SCHEMBL8462752 0.80 NLRP3 (0.39) NLRP3ANPEPCYP2C19ALOX15TSHR
SCHEMBL3474559 0.79 NLRP3 (0.52) NLRP3ALOX15TDP1ALDH1A1KDM4E
SCHEMBL6902097 0.79 ANPEP (0.52) NLRP3ANPEPCYP2C19ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021591-A Herbicides THE DOW CHEMICAL COMPANY (US) 1991-06-04 US disclosed
EP-0142152-B1 Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil THE DOW CHEMICAL COMPANY (US) 1991-03-20 EP disclosed
US-4997940-A Herbicides THE DOW CHEMICAL COMPANY (US) 1991-03-05 US disclosed
US-4992091-A Herbicides THE DOW CHEMICAL COMPANY (US) 1991-02-12 US disclosed
US-4983772-A 2-Methoxy-6-trifluoromethylaniline and 2,6-difluoro-3-methylaniline, intermediates to triazolo/1,5-a/pyrmidine-2-sulfonamide herbicides THE DOW CHEMICAL COMPANY (US) 1991-01-08 US disclosed
US-4954163-A PRE-AND POSTEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1990-09-04 US disclosed
US-4892946-A HERBICIDES, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-01-09 US disclosed
US-4886883-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1989-12-12 US disclosed
US-4822404-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1989-04-18 US disclosed
US-4818273-A Substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides, compositions containing them, and their utility as herbicides THE DOW CHEMICAL COMPANY (US) 1989-04-04 US disclosed
EP-0023141-A2 Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-28 EP disclosed
US-4231784-A PRE- AND POSTEMERGENCE HERBICIDES; PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-11-04 US disclosed
US-4214890-A PRE- AND POST-EMERGENCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-29 US disclosed
EP-0013480-A2 Herbicidal pyridinesulfonamides, preparation and use thereof and compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-23 EP disclosed
EP-0010560-A1 Herbicidal sulfonamides, their preparation, compositions containing them and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-05-14 EP disclosed
EP-0009419-A1 Agricultural sulfonamides, and preparation and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-04-02 EP disclosed
US-4190432-A CONTROLLING VOLUNTEER CORN IN SOYBEANS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-02-26 US disclosed
EP-0005986-A1 Herbicidal carbamimidothioates, preparation and use thereof and compositions containing said compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 1979-12-12 EP disclosed
US-4169719-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND CO. (US) 1979-10-02 US disclosed
US-4127405-A TRIAZINYL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-11-28 US disclosed