Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9145471 | 0.90 | ALDH1A1 (0.45) | ALDH1A1GAAPOLBUSP2KMT2A | |
| SCHEMBL9147454 | 0.88 | HPGD (0.50) | ALDH1A1GAAPOLBUSP2KMT2A | |
| SCHEMBL9146108 | 0.87 | ALDH1A1 (0.50) | ALDH1A1GAAPOLBUSP2KMT2A | |
| SCHEMBL9146890 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAAPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL15337535 | 0.80 | REN (0.46) | ALDH1A1GAAPOLBUSP2KMT2A | |
| SCHEMBL89670 | 0.78 | REN (0.54) | ALDH1A1POLBUSP2KMT2ACYP1A2 | |
| SCHEMBL1654900 | 0.78 | PDE3B (0.48) | ALDH1A1GAAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL4970309 | 0.78 | ALDH1A1 (0.48) | ALDH1A1GAAPOLBKMT2ATSHR | |
| SCHEMBL9144980 | 0.77 | HTT (0.65) | ALDH1A1POLBUSP2KMT2ACYP1A2 | |
| SCHEMBL4970308 | 0.76 | AKR1B1 (0.52) | ALDH1A1KMT2ASMN1; SMN2CYP1A2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432893-A2 | Benzoxazine derivatives, their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |