Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10333899 | 0.93 | CA12 (0.37) | ALDH1A1LMNAUSP2CYP2C19KDM4E | |
| SCHEMBL9682755 | 0.83 | CA9 (0.42) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL9845601 | 0.82 | ALDH1A1 (0.57) | ALDH1A1LMNACYP2C19MAPTKDM4E | |
| SCHEMBL11728360 | 0.81 | ALDH1A1 (0.58) | ALDH1A1LMNACYP2C19MAPTKDM4E | |
| SCHEMBL9770940 | 0.77 | ALDH1A1 (0.36) | ALDH1A1CYP2C19MAPTKDM4E | |
| SCHEMBL10334223 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4E | |
| SCHEMBL5933663 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNACYP2C19MAPTKDM4E | |
| SCHEMBL9681285 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTKDM4EHPGD | |
| SCHEMBL11728138 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4E | |
| SCHEMBL11729050 | 0.71 | ALDH1A1 (0.43) | ALDH1A1LMNACYP2C19MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933166-A | PHTHALIMIDE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1990-06-12 | — | — | US | claimed |
| EP-0312763-A1 | Methods and compositions for protecting crop plants from undesirable effects of insecticidal compounds and herbicidal compounds | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | claimed |
| US-4017299-A | Phthalimide derivatives as plant growth regulants | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | claimed |
| US-5102447-A | Applying 1-(3-chlorophthalimido)cyclohexanecarboxamide to the roots, seeds, leaves or soil surrounding crops to prevent phytotoxic effects of terbufos | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| US-4933166-A | PHTHALIMIDE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0312762-A1 | Method of safening fungicidal compositions thereof | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0312763-A1 | Methods and compositions for protecting crop plants from undesirable effects of insecticidal compounds and herbicidal compounds | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |