Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18802713 | 0.83 | GABRA1 (0.38) | TSHRESR1ESR2 | |
| SCHEMBL9906173 | 0.79 | SCN5A (0.47) | MEN1KMT2ATSHRNPSR1SCN5A | |
| SCHEMBL19204248 | 0.79 | SCN5A (0.47) | MEN1KMT2ATSHRNPSR1SCN5A | |
| SCHEMBL24783773 | 0.79 | — | — | |
| SCHEMBL19519036 | 0.79 | CA2 (0.38) | — | |
| SCHEMBL18802841 | 0.78 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL9906164 | 0.77 | KMT2A (0.60) | MEN1KMT2ATSHRNPSR1ESR1 | |
| SCHEMBL12224193 | 0.77 | KMT2A (0.60) | MEN1KMT2ATSHRNPSR1ESR1 | |
| SCHEMBL16770811 | 0.76 | TSHR (0.40) | MEN1KMT2ATSHRCNR2CNR1 | |
| SCHEMBL18802711 | 0.76 | ESR1 (0.33) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |