SCHEMBL9845707

SCHEMBL9845707

O=C(Cc1ccc(Cl)cc1)N(CC(Cl)(Cl)Cl)c1ccc(Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.57
CNR1 P21554 1/20 0.52
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
CYP3A4 P08684 3/20 0.41
BCL2A1 Q16548 3/20 0.40
CTBP2 P56545 1/20 0.39
PDK2 Q15119 1/20 0.39
PDK4 Q16654 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL657249 0.76 CNR2 (0.56) CNR2CNR1RAB9ANPC1CYP3A4
SCHEMBL656829 0.73 CNR2 (0.52) CNR2CNR1RAB9ANPC1L3MBTL1
SCHEMBL3766395 0.73 CNR2 (0.40) CNR2CNR1RAB9ANPC1PDK2
SCHEMBL27983581 0.73 CNR2 (0.52) CNR2CNR1RAB9ANPC1L3MBTL1
SCHEMBL15064734 0.73 CNR2 (1.00) CNR2CNR1CYP3A4
SCHEMBL5971374 0.73 CNR2 (0.55) CNR2CNR1RAB9ANPC1CTBP2
SCHEMBL656732 0.71 CNR2 (0.58) CNR2CNR1RAB9ANPC1CYP3A4
SCHEMBL657435 0.71 HDAC1 (0.56) CNR2CNR1L3MBTL1
SCHEMBL3846324 0.70 CNR2 (0.52) CNR2CNR1L3MBTL1
SCHEMBL15438012 0.70 L3MBTL1 (0.58) CNR2CNR1RAB9ANPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0407086-A2 Melamine-containing photoresists of improved sensitivity ROHM AND HAAS COMPANY (US) 1991-01-09 EP disclosed