Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845864 | 0.87 | SMN1; SMN2 (0.39) | ACHENPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9845893 | 0.84 | SMN1; SMN2 (0.36) | ACHENPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9845863 | 0.84 | SMN1; SMN2 (0.36) | ACHENPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9828723 | 0.79 | ACHE (0.46) | ACHESMN1; SMN2 | |
| SCHEMBL9828719 | 0.79 | ACHE (0.46) | ACHESMN1; SMN2 | |
| SCHEMBL9845900 | 0.77 | ACHE (0.38) | ACHENPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9353120 | 0.77 | EPHX1 (0.43) | ACHEEPHX1 | |
| SCHEMBL9830496 | 0.74 | SMN1; SMN2 (0.44) | ACHESMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9830489 | 0.74 | SMN1; SMN2 (0.44) | ACHESMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL337339 | 0.74 | ACHE (0.53) | ACHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414533-A1 | Use of iodopropargyl esters of alpha-amino acid derivatives as antimicrobial agents | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | claimed |