Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 12/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830496 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2PPARGPPARAPLA2G2APLA2G5 | |
| SCHEMBL9828991 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARGPPARAPLA2G2APLA2G5 | |
| SCHEMBL9828998 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARGPPARAPLA2G2APLA2G5 | |
| SCHEMBL9828719 | 0.85 | ACHE (0.46) | SMN1; SMN2ACHE | |
| SCHEMBL9828723 | 0.85 | ACHE (0.46) | SMN1; SMN2ACHE | |
| SCHEMBL10481483 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2PPARGPPARAPLA2G2APLA2G5 | |
| SCHEMBL10481485 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2PPARGPPARAPLA2G2APLA2G5 | |
| SCHEMBL509967 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2PPARGPPARAPLA2G2APLA2G5 | |
| SCHEMBL1287155 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2PPARGPPARAPLA2G2APLA2G5 | |
| SCHEMBL7755148 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2PPARGPPARAPLA2G2APLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |