Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845969 | 0.88 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL9845983 | 0.77 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL9835656 | 0.69 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL9836014 | 0.63 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9845990 | 0.62 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10483042 | 0.61 | — | — | |
| SCHEMBL12221042 | 0.58 | ALDH1A1 (0.48) | ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL28935210 | 0.58 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL289021 | 0.57 | — | — | |
| SCHEMBL6573461 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414952-A1 | Dithiolane derivatives | NIHON NOHYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | claimed |
| JP-1242580-A | — | — | None | — | — | JP | disclosed |
| EP-0414952-A1 | Dithiolane derivatives | NIHON NOHYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| JP-H01242580-A | DITHIOLANE DERIVATIVE | NIPPON NOHYAKU CO LTD | 1989-09-27 | — | — | JP | disclosed |