Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835656 | 0.74 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL9845949 | 0.62 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL131067 | 0.60 | SMN1; SMN2 (0.44) | ALDH1A1HPGDMAPTL3MBTL1KMT2A | |
| SCHEMBL16822338 | 0.59 | ALDH1A1 (0.43) | ALDH1A1HPGDL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL908743 | 0.57 | SLC18A3 (0.53) | ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL9836014 | 0.57 | ALDH1A1 (0.54) | ALDH1A1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL1799606 | 0.57 | SMN1; SMN2 (0.46) | ALDH1A1HPGDL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL9845969 | 0.57 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL7593164 | 0.56 | PIM1 (0.35) | ALDH1A1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL11039721 | 0.56 | PIK3CD (0.43) | ALDH1A1PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414952-A1 | Dithiolane derivatives | NIHON NOHYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | claimed |