Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895025 | 0.84 | MME (0.46) | TSHRGRIA2GRIA4ALDH1A1L3MBTL1 | |
| SCHEMBL9845999 | 0.83 | FFAR1 (0.41) | TSHRALDH1A1CYP2C9L3MBTL1TDP1 | |
| SCHEMBL4017672 | 0.83 | F10 (0.38) | GRIA2GRIA4ALDH1A1CYP2C9L3MBTL1 | |
| SCHEMBL1369868 | 0.83 | ALOX5AP (0.42) | GRIA2GRIA4ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL1372453 | 0.82 | AGTR1 (0.45) | TSHRGRIA2GRIA4ALDH1A1CYP2C9 | |
| SCHEMBL1373247 | 0.81 | LTB4R2 (0.40) | TSHRGRIA2GRIA4MMEFFAR1 | |
| SCHEMBL1369710 | 0.80 | AR (0.43) | PPARG | |
| SCHEMBL9846022 | 0.79 | FFAR1 (0.47) | TSHRGRIA2GRIA4MMEFFAR1 | |
| SCHEMBL1370358 | 0.78 | MME (0.47) | GRIA2GRIA4ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL27962068 | 0.78 | MME (0.47) | GRIA2GRIA4ALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424317-A2 | Pyrimidines | CIBA-GEIGY AG (CH) | 1991-04-24 | — | — | EP | disclosed |