Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539561 | 0.90 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9543200 | 0.89 | PDE4A (0.39) | AGTR1AGTR2 | |
| SCHEMBL9846055 | 0.85 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9846125 | 0.84 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9846061 | 0.83 | AGTR1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL9846041 | 0.82 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9846014 | 0.80 | — | — | |
| SCHEMBL9845994 | 0.79 | CYP19A1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9233107 | 0.78 | PDE4A (0.47) | AGTR1AGTR2 | |
| SCHEMBL9846079 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424317-A2 | Pyrimidines | CIBA-GEIGY AG (CH) | 1991-04-24 | — | — | EP | claimed |