Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846039 | 0.89 | PPARG (0.45) | APLNRPPARGAGTR1AGTR2ACHE | |
| SCHEMBL9846024 | 0.86 | PPARG (0.47) | APLNRPPARGAGTR1AGTR2ACHE | |
| SCHEMBL9846092 | 0.84 | PPARG (0.45) | APLNRPPARGAGTR1AGTR2ACHE | |
| SCHEMBL9846040 | 0.84 | APLNR (0.38) | APLNRPPARGAGTR1AGTR2ACHE | |
| SCHEMBL9846015 | 0.83 | PPARG (0.45) | APLNRPPARGAGTR1AGTR2FFAR1 | |
| SCHEMBL9846038 | 0.81 | PPARG (0.41) | APLNRPPARGAGTR1AGTR2ACHE | |
| SCHEMBL9311025 | 0.81 | PPARG (0.49) | APLNRPPARGAGTR1AGTR2FFAR1 | |
| SCHEMBL9846027 | 0.79 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9308844 | 0.79 | PPARG (0.45) | APLNRPPARGAGTR1AGTR2ACHE | |
| SCHEMBL9846117 | 0.78 | APLNR (0.44) | APLNRCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424317-A2 | Pyrimidines | CIBA-GEIGY AG (CH) | 1991-04-24 | — | — | EP | disclosed |