Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573402 | 0.85 | ESR2 (0.54) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL27955134 | 0.83 | ESR2 (0.57) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL1713 | 0.80 | ESR2 (0.67) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL31410710 | 0.79 | ESR2 (0.76) | ESR2FFAR1AKR1B1PTPN5GSK3B | |
| SCHEMBL31772593 | 0.79 | ESR2 (0.59) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL360601 | 0.79 | ESR2 (0.59) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL357 | 0.79 | ESR2 (0.59) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL31124937 | 0.79 | ESR2 (0.59) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL7867991 | 0.79 | ESR2 (0.59) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL9542596 | 0.79 | ESR2 (0.59) | ESR2MMEFFAR1AKR1B1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424317-A2 | Pyrimidines | CIBA-GEIGY AG (CH) | 1991-04-24 | — | — | EP | disclosed |