Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024906 | 0.80 | GRM5 (0.44) | ADORA2AADORA1SMN1; SMN2GRM5PTGER1 | |
| SCHEMBL13562462 | 0.79 | SMN1; SMN2 (0.42) | ADORA2AADORA1SMN1; SMN2TAAR1MAPT | |
| SCHEMBL22837182 | 0.78 | MPO (0.44) | ADORA2ASMN1; SMN2MPOGRM5MAPT | |
| SCHEMBL14082023 | 0.78 | CCR1 (0.52) | SMN1; SMN2MPOGRM5ALDH1A1KMT2A | |
| SCHEMBL9026500 | 0.77 | SMN1; SMN2 (0.50) | ADORA2AADORA1SMN1; SMN2TAAR1MAPT | |
| SCHEMBL13562467 | 0.75 | SLC5A2 (0.47) | ADORA2AADORA1SMN1; SMN2TAAR1MAPT | |
| SCHEMBL9027227 | 0.75 | PTGER1 (0.39) | ADORA2AADORA1SMN1; SMN2TAAR1PTGER1 | |
| SCHEMBL13562419 | 0.74 | CYP1A2 (0.46) | ADORA2AADORA1SMN1; SMN2TAAR1ALDH1A1 | |
| SCHEMBL1563589 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2MPOGRM5ALDH1A1KMT2A | |
| SCHEMBL21548843 | 0.73 | SMN1; SMN2 (0.60) | ADORA2AADORA1SMN1; SMN2TAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459662-A1 | Fungicidal compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |