Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR39 | O43194 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025927 | 0.86 | GRM5 (0.38) | GRM5FFAR1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9025837 | 0.83 | GRM5 (0.43) | GRM5FFAR1PTGER1KMT2ASMN1; SMN2 | |
| SCHEMBL9026091 | 0.82 | FFAR1 (0.44) | GRM5FFAR1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9500899 | 0.81 | BRD4 (0.41) | GRM5FFAR1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9846059 | 0.80 | ADORA2A (0.46) | GRM5ADORA2AADORA1PTGER1KMT2A | |
| SCHEMBL3787471 | 0.76 | CYP1A2 (0.37) | PTGER1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL9586353 | 0.76 | GRM5 (0.42) | GRM5FFAR1GPR39 | |
| SCHEMBL9369946 | 0.76 | GRM5 (0.46) | GRM5FFAR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9027236 | 0.75 | FFAR1 (0.40) | GRM5FFAR1KMT2ANPC1LMNA | |
| SCHEMBL10368628 | 0.75 | GRM5 (0.39) | GRM5FFAR1ALDH1A1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459662-B1 | Fungicidal compounds | ZENECA LTD (GB) | 1996-08-21 | — | — | EP | disclosed |
| US-5185339-A | FUNGICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0459662-A1 | Fungicidal compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |