Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846426 | 0.82 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DRARA | |
| SCHEMBL9846244 | 0.81 | APOBEC3A (0.30) | — | |
| SCHEMBL9846119 | 0.75 | TTR (0.30) | RARARARBRARG | |
| SCHEMBL9846121 | 0.75 | TTR (0.30) | RARARARBRARG | |
| SCHEMBL9846220 | 0.73 | ALOX5 (0.32) | — | |
| SCHEMBL9846102 | 0.72 | GRIN2D (0.36) | — | |
| SCHEMBL9432051 | 0.71 | APOBEC3A (0.33) | — | |
| SCHEMBL9432058 | 0.70 | TAAR1 (0.50) | — | |
| SCHEMBL9846324 | 0.68 | — | — | |
| SCHEMBL9846323 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |