Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846119 | 1.00 | TTR (0.30) | TTRRARARARBRARG | |
| SCHEMBL9846323 | 0.81 | — | — | |
| SCHEMBL9846324 | 0.81 | — | — | |
| SCHEMBL9846106 | 0.75 | PDE4A (0.34) | RARARARBRARG | |
| SCHEMBL9846426 | 0.73 | PDE4A (0.35) | RARARARBRARG | |
| SCHEMBL9846156 | 0.73 | ALOX5 (0.31) | — | |
| SCHEMBL9846211 | 0.72 | ELANE (0.31) | — | |
| SCHEMBL9432062 | 0.72 | ELANE (0.31) | — | |
| SCHEMBL9267418 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL9846194 | 0.68 | PDE3B (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |