Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 7/20 | 0.43 |
| ▸ | METAP1 | P53582 | 7/20 | 0.43 |
| ▸ | CBFB | Q13951 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846300 | 0.83 | NPC1 (0.55) | BTKNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL29415394 | 0.78 | KDM4E (0.50) | BTKNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL673163 | 0.78 | KDM4E (0.50) | BTKNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL5396521 | 0.77 | KDM4E (0.50) | BTKNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL27967298 | 0.76 | NPC1 (0.49) | BTKNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL29756476 | 0.76 | NPC1 (0.49) | BTKNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL5390769 | 0.73 | NPY5R (0.53) | BTKNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL2721741 | 0.73 | CBFB (0.52) | BTKNPC1RAB9ALMNAALDH1A1 | |
| Boric Acid SCHEMBL31103495 | 0.72 | NPC1 (0.45) | BTKNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL12075237 | 0.71 | KDM4E (0.60) | BTKNPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431421-A2 | Heteroarylsubstituted pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | claimed |
| EP-0431421-A2 | Heteroarylsubstituted pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |