Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 7/20 | 0.50 |
| ▸ | METAP1 | P53582 | 7/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5390769 | 0.89 | NPY5R (0.53) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5396521 | 0.86 | KDM4E (0.50) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9846148 | 0.83 | BTK (0.46) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2721741 | 0.82 | CBFB (0.52) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10838008 | 0.78 | KDM4E (0.50) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1988750 | 0.77 | KDM4E (0.58) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13611987 | 0.75 | LMNA (0.54) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL308319 | 0.74 | GSK3B (0.61) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29470995 | 0.74 | GSK3B (0.61) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5386067 | 0.73 | GSK3B (0.51) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431421-A2 | Heteroarylsubstituted pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | claimed |
| US-7612010-B2 | Use of metal complex compounds as oxidation catalysts | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20080081908-A1 | Use of metal complex compounds as oxidation catalysts | SCHLINGLOFF GUNTHER | 2008-04-03 | — | — | US | disclosed |
| US-20080000032-A1 | Use of Metal Complexes Having Bispyridylpyrimidine or Bispyridyltriazine Ligands as Catalysts for Reactions With Peroxy Compounds for Bleaching Coloured Stains on Hard Surfaces | CIBA SPECIALTY CHEMICALS CORP. | 2008-01-03 | — | — | US | disclosed |
| US-7291584-B2 | Use of metal complex compounds as oxidation catalysts | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-11-06 | — | — | US | disclosed |
| US-20070032656-A1 | Use of metal complex compounds as oxidation catalysts | SCHLINGLOFF GUNTHER | 2007-02-08 | — | — | US | disclosed |
| EP-0431421-A2 | Heteroarylsubstituted pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080000032-A1 | Use of Metal Complexes Having Bispyridylpyrimidine or Bispyridyltriazine Ligands as Catalysts for Reactions With Peroxy Compounds for Bleaching Coloured Stains on Hard Surfaces | TYR, DPY30, TET2 | NPC1 4824/4885LMNA 4192/4885RAB9A 2931/4885 |
| US-20080081908-A1 | Use of metal complex compounds as oxidation catalysts | AP1M1, MLX, SOD1 | NPC1 785/4885LMNA 1750/4885RAB9A 1411/4885 |
| US-20070032656-A1 | Use of metal complex compounds as oxidation catalysts | AP1M1, MLX, SOD1 | NPC1 785/4885LMNA 1750/4885RAB9A 1411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.