Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573692 | 0.84 | MAPT (0.39) | ALDH1A1GLAL3MBTL1ELANEKDM4E | |
| SCHEMBL9278111 | 0.75 | PIK3CD (0.44) | PIK3CDPIK3CBPIK3CGPARP1ALDH1A1 | |
| SCHEMBL14610912 | 0.69 | TP53 (0.42) | FBP1F2RL3ELANETP53AGPAT2 | |
| SCHEMBL9846224 | 0.64 | PARP1 (0.37) | PIK3CDPIK3CBPIK3CGPARP1ALDH1A1 | |
| SCHEMBL9846133 | 0.64 | PIK3CD (0.42) | PIK3CDPIK3CBPIK3CGPARP1ALDH1A1 | |
| SCHEMBL5542360 | 0.63 | F2RL3 (0.45) | PIK3CDPIK3CBPIK3CGFBP1F2RL3 | |
| SCHEMBL9166348 | 0.62 | IDH1 (0.37) | PIK3CDPIK3CBPIK3CGPARP1ALDH1A1 | |
| SCHEMBL9166681 | 0.62 | PIK3CD (0.41) | PIK3CDPIK3CBPIK3CGPARP1ALDH1A1 | |
| SCHEMBL9442179 | 0.61 | ELANE (0.36) | ALDH1A1GLAL3MBTL1ELANEKDM4E | |
| SCHEMBL9281338 | 0.61 | PIK3CD (0.44) | PIK3CDPIK3CBALDH1A1GLAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |